In a daring operation involving sewers, cardboard boxes, and trucks; Ntagbu, the village rat, rescues Anya Ukwu and the town rats when they face the threat of death by clobbering, poisonings, and flooded sewers.

While the rats are the main actors, The Village Rat & The Town Rat also illustrates the folly of humans who build houses in their ancestral villages that are unoccupied for several years, effectively turning them into rat castles.